Objectives: We present an up-to-date review of STRUCTURE software: one of the most widely used population analysis tools that allows researchers to assess patterns of genetic structure in a set of samples. 3Genomics Medicine Group, CIBERER, University of Santiago de Compostela, Santiago de Compostela, Spain.2Forensic Genetics Unit, Institute of Legal Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain.1Universidad Tecnológica de Pereira, Pereira, Colombia.Liliana Porras-Hurtado 1,2†, Yarimar Ruiz 2†, Carla Santos 2†, Christopher Phillips 2*, Ángel Carracedo 2,3 and Maria V.